publications

2024

1. NAACL 2025

   VividMed: Vision Language Model with Versatile Visual Grounding for Medicine

   Lingxiao Luo*, Bingda Tang*, Xuanzhong Chen, Rong Han, and Ting Chen

   2024

   Abs arXiv Code

   Recent advancements in Vision Language Models (VLMs) have demonstrated remarkable promise in generating visually grounded responses. However, their application in the medical domain is hindered by unique challenges. For instance, most VLMs rely on a single method of visual grounding, whereas complex medical tasks demand more versatile approaches. Additionally, while most VLMs process only 2D images, a large portion of medical images are 3D. The lack of medical data further compounds these obstacles. To address these challenges, we present VividMed, a vision language model with versatile visual grounding for medicine. Our model supports generating both semantic segmentation masks and instance-level bounding boxes, and accommodates various imaging modalities, including both 2D and 3D data. We design a three-stage training procedure and an automatic data synthesis pipeline based on open datasets and models. Besides visual grounding tasks, VividMed also excels in other common downstream tasks, including Visual Question Answering (VQA) and report generation. Ablation studies empirically show that the integration of visual grounding ability leads to improved performance on these tasks.

2. Preprint

   CORE4D: A 4D Human-Object-Human Interaction Dataset for Collaborative Object REarrangement

   Chengwen Zhang*, Yun Liu*, Ruofan Xing, Bingda Tang, Bowen Yang, and Li Yi

   2024

   Abs arXiv Code

   Understanding how humans cooperatively rearrange household objects is critical for VR/AR and human-robot interaction. However, in-depth studies on modeling these behaviors are under-researched due to the lack of relevant datasets. We fill this gap by presenting CORE4D, a novel large-scale 4D human-object-human interaction dataset focusing on collaborative object rearrangement, which encompasses diverse compositions of various object geometries, collaboration modes, and 3D scenes. With 1K human-object-human motion sequences captured in the real world, we enrich CORE4D by contributing an iterative collaboration retargeting strategy to augment motions to a variety of novel objects. Leveraging this approach, CORE4D comprises a total of 11K collaboration sequences spanning 3K real and virtual object shapes. Benefiting from extensive motion patterns provided by CORE4D, we benchmark two tasks aiming at generating human-object interaction: human-object motion forecasting and interaction synthesis. Extensive experiments demonstrate the effectiveness of our collaboration retargeting strategy and indicate that CORE4D has posed new challenges to existing human-object interaction generation methodologies.

3. Preprint

   Jailbreaking Large Language Models Through Alignment Vulnerabilities in Out-of-Distribution Settings

   Yue Huang, Jingyu Tang, Dongping Chen, Bingda Tang, Yao Wan, Lichao Sun, Philip S. Yu, and Xiangliang Zhang

   2024

   Abs arXiv

   Recently, Large Language Models (LLMs) have garnered significant attention for their exceptional natural language processing capabilities. However, concerns about their trustworthiness remain unresolved, particularly in addressing "jailbreaking" attacks on aligned LLMs. Previous research predominantly relies on scenarios with white-box LLMs or specific and fixed prompt templates, which are often impractical and lack broad applicability. In this paper, we introduce a straightforward and novel method, named ObscurePrompt, for jailbreaking LLMs, inspired by the observed fragile alignments in Out-of-Distribution (OOD) data. Specifically, we first formulate the decision boundary in the jailbreaking process and then explore how obscure text affects LLM’s ethical decision boundary. ObscurePrompt starts with constructing a base prompt that integrates well-known jailbreaking techniques. Powerful LLMs are then utilized to obscure the original prompt through iterative transformations, aiming to bolster the attack’s robustness. Comprehensive experiments show that our approach substantially improves upon previous methods in terms of attack effectiveness, maintaining efficacy against two prevalent defense mechanisms. We believe that our work can offer fresh insights for future research on enhancing LLM alignment.

4. IMWUT 2024

   CalibRead: Unobtrusive Eye Tracking Calibration from Natural Reading Behavior

   Chang Liu, Chun Yu, Xiangyang Wang, Jianxiao Jiang, Tianao Yang, Bingda Tang, Yingtian Shi, Liang Chen, and Yuanchun Shi

   2024
5. Preprint

   Building Universal Foundation Models for Medical Image Analysis with Spatially Adaptive Networks

   Lingxiao Luo, Xuanzhong Chen, Bingda Tang, Xinsheng Chen, Rong Han, Chengpeng Hu, Yujiang Li, and Ting Chen

   2024

   Abs arXiv Code

   Recent advancements in foundation models, typically trained with self-supervised learning on large-scale and diverse datasets, have shown great potential in medical image analysis. However, due to the significant spatial heterogeneity of medical imaging data, current models must tailor specific structures for different datasets, making it challenging to leverage the abundant unlabeled data. In this work, we propose a universal foundation model for medical image analysis that processes images with heterogeneous spatial properties using a unified structure. To accomplish this, we propose spatially adaptive networks (SPAD-Nets), a family of networks that dynamically adjust the structures to adapt to the spatial properties of input images, to build such a universal foundation model. We pre-train a spatial adaptive visual tokenizer (SPAD-VT) and then a spatial adaptive Vision Transformer (SPAD-ViT) via masked image modeling (MIM) on 55 public medical image datasets. The pre-training data comprises over 9 million image slices, representing the largest, most comprehensive, and most diverse dataset to our knowledge for pre-training universal foundation models for medical image analysis. The experimental results on downstream medical image classification and segmentation tasks demonstrate the superior performance and label efficiency of our model.